6 edition of Signaling Networks and Cell Cycle Control found in the catalog.
by Humana Press
Written in English
|The Physical Object|
|Number of Pages||592|
Cancer, which has become the second-most prevalent health issue globally, is essentially a malfunction of cell signaling. Understanding how the intricate signaling networks of cells and tissues allow cancer to thrive - and how they can be turned into potent weapons against it - is the key to managing cancer in the clinic and improving the outcome of cancer therapies. Chapter Signaling Networks Basic Introduction 2 Overview Introduction Basic structure & operations References Book: R.A. Weinberg, The Biology of Cancer () Review: Yarden & Sliwkowski Nat Rev Mol Cell Biology 2: ,
Aspects of developmental biology, the immune system, the nervous system, and plant biology are thus discussed in their broader biological context in chapters covering areas such as genome structure, gene expression, DNA rearrangements, the plasma membrane, cell . Production of two cells from one requires duplication of all molecules and organelles that compose each cell. DNA does not duplicate throughout the cycle but only during several hours in S-phase (Fig. 1). During S-phase, the DNAs of the , genes located on 23 pairs (in humans) of chromosomes are replicated, each in a timely fashion. This requires the ordered Cited by:
The book is essential reading for students learning about signal transduction for the first time. It will also be a vital reference for all cell, molecular, and developmental biologists and pharmacologists, neurobiologists, and immunologists studying processes regulated by . Xiong Y, Sheen J. Moving beyond translation: glucose-TOR signaling in the transcriptional control of cell cycle. Cell Cycle. ; – [PMC free article] Xiong Y, Sheen J. The role of target of rapamycin signaling networks in plant growth and metabolism. Plant Physiol. ; – [PMC free article]Cited by:
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Thus, Gutkind in Signaling Networks and Cell Cycle Control has his work cut out for him in the attempt to provide a thorough coverage of the vast array of signaling cascades responsible for virtually every cellular response.
It is an admirable effort, as a number of leaders from a broad range of signaling fields have been assembled to present the background and Author: Richard A. Cerione. In Signaling Networks and Cell Cycle Control: The Molecular Basis of Cancer and Other Diseases, leading scientists summarize this knowledge and describe the effort to design and synthesize inhibiting molecules, as well as to evaluate their biochemical and biological activities.
In Signaling Networks and Cell Cycle Control: The Molecular Basis of Cancer and Other Diseases, leading scientists summarize this knowledge and describe the effort to design and synthesize inhibiting molecules, as well as to evaluate their biochemical and biological activities.
They review the relevant cell surface receptors, their ligands, and 5/5(1). Read "Signaling Networks and Cell Cycle Control The Molecular Basis of Cancer and Other Diseases" by available from Rakuten Kobo.
Leading scientists summarize the latest findings on signal transduction and cell cycle regulation and describe the effor Brand: Humana Press.
Also examined are the latest findings on the components of novel signaling networks controlling the activity of nuclear transcription factors and cell cycle regulatory molecules.
Leading scientists summarize the latest findings on signal transduction and cell cycle regulation and describe the effort to design and synthesize inhibiting molecules, as well as to evaluate their biochemical and biological activities. They review the relevant cell surface receptors, their Price: $ Books Signaling Networks and Cell Cycle Control: The Molecular Basis of Cancer and Other Diseases (Cancer Drug Discovery and.
Get this from a library. Signaling networks and cell cycle control: the molecular basis of cancer and other diseases. [J Silvio Gutkind;]. In biology, cell signaling (cell signalling in British English) is part of any communication process that governs basic activities of cells and coordinates multiple-cell actions.
The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity, as well as normal tissue homeostasis. Get this from a library. Signaling networks and cell cycle control: the molecular basis of cancer and other diseases.
[J Silvio Gutkind;] -- The recent dramatic expansion of our knowledge about how cell surface receptors transmit signals to the nucleus, together with the identification of key signaling and cell-cycle-regulating molecules.
Signaling Networks and Cell Cycle Control J. Silvio Gutkind In recent years, following an explosion in the knowledge of how cell surface receptors transmit signals to the nucleus, it has been uncovered that a unique group of signaling molecules link each class of receptors to a variety of newly discovered kinase cascades.
Annual Plant Reviews, Volume 33 Intracellular Signaling in Plants. An intriguing and important question in our understanding of plant developmental programming and responses to the environment is what kinds of strategies and mechanisms plant cells use for the transmission and the integration of various developmental and environmental signals.
Here, we summarize recent efforts in elucidating cell type-specific signaling, and in particular the role of protein abundances, signaling complexes and modules. We further discuss the potential of using synthetic biology approaches to decipher signaling networks.
Pathway Description: The G2/M DNA damage checkpoint serves to prevent the cell from entering mitosis (M-phase) with genomic DNA damage. Specifically, the activity of the Cyclin B-cdc2 (CDK1) complex is pivotal in regulating the G2-phase transition wherein cdc2 is maintained in an inactive state by the tyrosine kinases Wee1 and Myt1.
DNA damage signaling, checkpoint control, and the role of p (A) DNA damage signaling pathways. In response to genotoxic stress by chemotherapeutic agents, cells activate complex signaling networks that control DNA repair and cell cycle arrest or initiate apoptosis if.
In Andrew Murray and Tim Hunt published a terrific textbook titled The Cell Cycle: An Introduction. It was a timely book, coming right on the heels of the discovery that cyclin-dependent kinases (Cdks) drive cell-cycle transitions in diverse eukaryotes.
It was a good read too, using clear writing and an emphasis on concepts to effectively convey the sense of an Author: James E.
Ferrell. Cell cycle control, replication, mitosis, meiosis, and checkpoint controls. Programmed cell death and apoptosis. Regulation of cell growth, proliferation, and survival, particularly in the context of stress or transformation.
Signaling pathways regulating transcription and other cellular processes. The Cell A Molecular Approach. The Cell is focused on the molecular biology of cells as a unifying theme, with specialized topics discussed throughout the book as examples of more general principles.
DNA rearrangements, the plasma membrane, cell signaling, and the cell cycle. Author(s Cellular Organization, Secretion and Endocytosis.
Cell Cycle Control. Results and Problems in Cell Differentiation (Book 22) Thanks for Sharing. You submitted the following rating and review. We'll Brand: Springer Berlin Heidelberg.
The Cell Cycle, Principles of Control. David O. Morgan. Article (PDF Available) in Integrative and Comparative Biology 47(5) June with 4, ReadsAuthor: Jane Lubischer. Gene expression and cell cycle control by kinases in response to stress. (BIO) Study of the role of chromatin in regulating induced transcription in response to heat stress.
(BFU) Genomic instability. (Consolider) Cell cycle control by p38 MAPK in mammalian cells. (BFU) The interactive pathway diagrams associated with these topics have been assembled by CST scientists and outside experts to provide succinct and current overviews of selected signaling pathways.
Protein nodes in each interactive pathway diagram are linked to specific antibody product information or, optionally, to protein-specific listings in.Signal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events, most commonly protein phosphorylation catalyzed by protein kinases, which ultimately results in a cellular ns responsible for detecting stimuli are generally termed receptors, although in some cases the term sensor is used.